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Test Code PYR Pyruvic Acid, Blood

Important Note

Order GO23910 Generic Orderable/Misc Test

Reporting Name

Pyruvic Acid, B

Useful For

Screening for possible disorders of mitochondrial metabolism, when used in conjunction with blood lactate collected at the same time, to determine the lactate-to-pyruvate ratio

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole blood


Additional Testing Requirements


This test does not calculate the lactate:pyruvate ratio. If you would like the lactate:pyruvate ratio, order LAPYP / Lactate Pyruvate Panel, Plasma.



Specimen Required


Call 800-533-1710 or 507-266-5700 to order special collection tube.

 

Patient Preparation: Fasting (at least 4 hours)

Supplies: Perchloric Acid-Pyruvate Tube (T012)

Container/Tube: Special collection tube containing 2.5 mL of 6% perchloric acid

Specimen Volume: Exactly 1 mL

Collection Instructions:

1. Special collection tube must be prechilled prior to collection.

2. Draw enough blood directly into syringe to add exactly 1 mL of blood to the prechilled special collection tube.

3. Taking care to not spill any of the preservative, cautiously remove the cap from the tube.

4. Immediately transfer blood, once drawn, to the prechilled, special collection tube, recap, and shake vigorously to mix.

Additional Information:

1. Check expiration date before using. Supplied collection tube expires 14 months after preparation.

2. If perchloric acid (preservative) spills, obtain a new, prechilled tube.


Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Refrigerated 15 days PYRUVATE

Reference Values

0.08-0.16 mmol/L

 

NIH Unit

0.7-1.4 mg/dL

Day(s) Performed

Monday, Thursday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84210

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PYR Pyruvic Acid, B 14121-8

 

Result ID Test Result Name Result LOINC Value
8657 Pyruvic Acid, B 14121-8
7729 Pyruvic Acid, B 2905-8

Cautions

Correct specimen collection and handling is crucial to achieve reliable results.

 

Pyruvic acid levels alone have little clinical utility. Abnormal concentrations of pyruvic acid and lactate-to-pyruvate (L:P) ratios are not diagnostic for a particular disorder but must be interpreted in the context of the patient's clinical presentation and other laboratory studies. The determination of pyruvic acid is of diagnostic value when lactic acid is measured and the L:P ratio is established in the same specimen.

 

When comparing blood and cerebrospinal fluid (CSF) L:P ratios, blood and CSF specimens should be collected at the same time.

Report Available

2 to 5 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK

NY State Approved

Yes

Method Name

Spectrophotometry (SP)

Secondary ID

8657