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Test Code LAB800 Parvovirus B19 Antibodies, IgG and IgM, Serum


Ordering Guidance


This test is intended for patients with at least 7 days of symptoms or asymptomatic individuals with recent exposure to parvovirus B19.

 

For patients with acute, symptomatic presentation, order either PARVP / Parvovirus B19, Molecular Detection, PCR, Plasma or PARVO / Parvovirus B19, Molecular Detection, PCR, Varies.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Information: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

48395

Useful For

Serologic detection of recent or past parvovirus B19 infection

Profile Information

Test ID Reporting Name Available Separately Always Performed
PARVG Parvovirus B19 Ab, IgG, S No Yes
PARVM Parvovirus B19 Ab, IgM, S No Yes
PARVN Parvovirus B19 Ab Interpretation No Yes

Method Name

PARVG, PARVM: Enzyme Immunoassay (EIA)

PARVN: Technical Interpretation

Reporting Name

Parvovirus B19 Ab, IgG and IgM, S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat-inactivated specimen Reject

Reference Values

IgG: Negative

IgM: Negative

Cautions

Specimens collected prior to seroconversion may yield negative IgM or IgG antibody results, while specimens collected after IgM antibody levels have begun to decline may yield negative IgM antibody results. Follow-up testing of convalescent samples may be beneficial to establish infection status.

 

The continued presence or absence of antibodies cannot be used to determine the success or failure of therapy.

 

Test results of specimens from immunocompromised patients may be difficult to interpret.

 

Testing should not be performed as a screening procedure for the general population. Testing should only be done when clinical evidence suggests the diagnosis of parvovirus B19-associated disease.

 

The performance of this test has not been established on neonates and immunocompromised patients.

 

Specimens containing antinuclear antibodies may produce equivocal or positive test results in the IgM assay.

 

Epstein-Barr virus-positive specimens may produce positive or equivocal test results in the IgM assay.

 

Assay performance characteristics have not been established for matrices other than serum.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86747 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PARVS Parvovirus B19 Ab, IgG and IgM, S 34950-6

 

Result ID Test Result Name Result LOINC Value
PARVG Parvovirus B19 Ab, IgG, S 29660-8
PARVM Parvovirus B19 Ab, IgM, S 40658-7
PARVN Parvovirus B19 Ab Interpretation 58737-8

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.