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Test Code LAB3336 Mumps Virus Antibody, IgM and IgG, Serum

Reporting Name

Mumps Ab, IgM and IgG, S

Useful For

Diagnosis of mumps virus infection

 

Determination of postimmunization immune response of individuals to the mumps vaccine

 

Documentation of previous infection with mumps virus in an individual with no previous record of immunization to mumps virus

Profile Information

Test ID Reporting Name Available Separately Always Performed
MMPM Mumps Ab, IgM, S Yes Yes
MPPG Mumps Ab, IgG, S Yes Yes

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

0.9 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

IgM:

Negative: Index value 0.00-0.79

Reference value applies to all ages.

 

IgG:

Vaccinated: Positive (≥1.1 AI)

Unvaccinated: Negative (≤0.8 AI)

Reference values apply to all ages.

Day(s) Performed

MMPM: Tuesday

MPPG: Monday through Friday

CPT Code Information

86735-Mumps, IgG

86735-Mumps, IgM

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MMPGM Mumps Ab, IgM and IgG, S 77250-9

 

Result ID Test Result Name Result LOINC Value
MUMP1 Mumps Ab, IgM, S 6478-2
MUMG Mumps Ab, IgG, S 6476-6
DEXM Index Value 25419-3
DEXG5 Mumps IgG Antibody Index 25418-5

Cautions

Serum specimens obtained during the acute phase of infection or soon after vaccination may be negative for IgM- or IgG-class antibodies by serological tests.

 

All positive IgM results must be interpreted cautiously as some false-positive results or heterotypical responses of the IgM have been seen in the serum of pregnant women or in patients with an acute infection caused by cytomegalovirus, herpes simplex virus, measles, rubella, or parvovirus.

 

Testing for IgM-class antibodies to mumps virus should be limited to patients with a clinically compatible disease.

 

Mumps virus shares antigenic relationships with other viruses of the paramyxovirus group; therefore, serologic cross-reactions are possible, but uncommon, with this test procedure.

 

Immunoglobulin G-class antibodies to mumps virus may be present in serum specimens from individuals who have received blood products within the past several months but have not been immunized or experienced past infection with this virus.

Report Available

1 to 7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Heat-inactivated specimen Reject

NY State Approved

Yes

Method Name

MMPM: Enzyme Immunoassay (EIA)

MPPG: Multiplex Flow Immunoassay

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.