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Test Code LAB3317 Herpes Simplex Virus (HSV), Molecular Detection, PCR, Blood


Ordering Guidance


If herpes simplex virus (HSV) is suspected in sources other than blood, order HSVPV / Herpes Simplex Virus (HSV), Molecular Detection, PCR, Varies.

 

If HSV is suspected in cerebrospinal fluid, order HSVC / Herpes Simplex Virus (HSV), Molecular Detection, PCR, Spinal Fluid.



Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 1 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Secondary ID

618308

Useful For

Aiding in the rapid diagnosis of disseminated disease due to herpes simplex virus (HSV)

 

Qualitative detection of HSV DNA

 

This test should not be used to screen asymptomatic patients.

Method Name

Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization

Reporting Name

Herpes Simplex Virus, PCR, B

Specimen Type

Whole Blood EDTA

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 7 days
  Frozen  7 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

HERPES SIMPLEX VIRUS (HSV)-1

Negative

 

HERPES SIMPLEX VIRUS (HSV)-2

Negative

Cautions

This test is intended for patients with evidence of disseminated disease due to herpes simplex virus (HSV). For patients with localized (eg, skin, genital) disease, a swab of suspect lesions should be collected and submitted for real-time polymerase chain reaction (PCR) analysis; HSVPV / Herpes Simplex Virus (HSV), Molecular Detection, PCR, Varies.

 

A negative result does not eliminate the possibility of HSV infection.

 

Although the reference value is typically "negative" for this assay, viral shedding may be detected in asymptomatic individuals. This assay is only to be used for patients with a clinical history and symptoms consistent with HSV infection and must be interpreted in the context of the clinical picture.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87529 x 2

87529 (if appropriate for government payers)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HSVPB Herpes Simplex Virus, PCR, B 93440-6

 

Result ID Test Result Name Result LOINC Value
618330 HSV 1 PCR, B 93439-8
618331 HSV 2 PCR, B 93438-0

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.