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Test Code LAB320 Protime/INR

Performing Lab

Arnot Ogden Medical Center/ Ira Davenport Memorial Hospital

Ordering Recommendations

Monitoring intensity of oral anticoagulant therapy when combined with INR reporting

Screening assay to detect deficiencies of 1 or more coagulation factors (factors I, II, V, VII, X) due to:
-Hereditary or acquired deficiency states
-Vitamin K deficiency
-Liver disease
-Specific coagulation factor inhibitors
-Screening assay to detect coagulation inhibition ("circulating anticoagulants") associated with:
-Specific coagulation factor inhibitors
-Lupus-like anticoagulant inhibitors (antiphospholipid antibodies)
-Nonspecific prothrombin time inhibitors (eg, monoclonal immunoglobulins, elevated fibrin degradation products)

Collect

Citrated Plasma

Collection Device

Sodium Citrate Blue Top Tube

Unacceptable Conditions

Refrigerated samples will be rejected.

Hemolyzed, clotted, short draw or overfilled specimens are not acceptable and must be redrawn.

Collection Instructions

  • Blue top tubes should NOT be the first tube drawn.
  • Tubes should be allowed to fill until the vacuum is exhausted and blood flow ceases.  

Pediatric Collection

Contact laboratory for pediatric draws.

Specimen Volume

FULL BLUE TOP TUBE

Stability (from collection to initiation)

Room Temp

24 Hours
Refrigerated
Unacceptable
Frozen 2 weeks (Must be spun and decanted)

Storage/Transport Temperature

Room Temp, or Frozen spun and separated

 

Remarks

TURN AROUND TIME

STAT

1 Hour
Routine 8 Hours

Methodology

Turbidimetric

Synonyms

Protime

PT

INR

Start Date

9/13/2017

Last Review Date

06/24/2025

7/3/25 AP

7/31/2025 JLH