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Test Code LAB1373 Epstein-Barr Virus DNA Detection and Quantification, Plasma


Shipping Instructions


1. Ship specimen frozen on dry ice.

2. If shipment will be delayed for more than 24 hours, freeze specimen at -20 to -80° C (up to 84 days) before shipment and transport on dry ice.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL Plasma

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot plasma into a plastic vial.


Secondary ID

615297

Useful For

Diagnosis of Epstein-Barr virus (EBV)-associated infectious mononucleosis in individuals with equivocal or discordant EBV serologic marker test results

 

Diagnosis of post-transplant lymphoproliferative disorders (PTLD), especially in EBV-seronegative organ transplant recipients receiving antilymphocyte globulin for induction immunosuppression and OKT-3 treatment for early organ rejection

 

Monitoring progression of EBV-associated PTLD in organ transplant recipients

 

This test should not be used to screen asymptomatic patients.

Method Name

Real-Time Polymerase Chain Reaction (PCR)

Reporting Name

EBV DNA Detect/Quant, P

Specimen Type

Plasma EDTA

Specimen Minimum Volume

Plasma: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Frozen (preferred) 84 days
  Refrigerated  6 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Undetected

Cautions

Serial determination of plasma specimens from organ transplant recipients may be necessary to monitor increasing (risk of development of post-transplant lymphoproliferative disorders) or decreasing (treatment efficacy) levels of Epstein-Barr virus (EBV) DNA.

 

Nonsymptomatic EBV viremia or viral shedding may occasionally occur in healthy individuals. Therefore, this test should be used only for patients with a clinical history and symptoms consistent with EBV infection. Test results must be interpreted in the context of patient's clinical history, signs, and symptoms.

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87799

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EBVQN EBV DNA Detect/Quant, P 43730-1

 

Result ID Test Result Name Result LOINC Value
615297 EBV DNA Detect/Quant, P 43730-1

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Microbiology Test Request (T244)

-General Request (T239)

-Kidney Transplant Test Request